Source:http://linkedlifedata.com/resource/pubmed/id/10650087
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
2000-3-6
|
pubmed:abstractText |
Three new ergostane-type steroids, 3beta-hydroxy-4alpha, 14alpha-dimethyl-5alpha-ergosta-8,24(28)-dien-11 -one (1); 3beta, 11alpha-dihydroxy-4alpha,14alpha-dimethyl-5alpha -ergosta-8, 24(28)-dien-7-one (2); and 3beta,7alpha-dihydroxy-4alpha, 14alpha-dimethyl-5alpha-ergosta-8,24(28)-dien-11 -one (3), were isolated, together with two known triterpenoids, wrightial and lup-20(30)-ene-3beta,29-diol from the whole herb of Euphorbia chamaesyce. Compound 3 showed a potent inhibitory effect on Epstein-Barr virus early antigen activation induced by the tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA).
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0163-3864
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
63
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
99-103
|
pubmed:dateRevised |
2000-12-18
|
pubmed:meshHeading |
pubmed-meshheading:10650087-Antigens, Viral,
pubmed-meshheading:10650087-Drug Screening Assays, Antitumor,
pubmed-meshheading:10650087-Euphorbiaceae,
pubmed-meshheading:10650087-Magnetic Resonance Spectroscopy,
pubmed-meshheading:10650087-Molecular Structure,
pubmed-meshheading:10650087-Spectrum Analysis,
pubmed-meshheading:10650087-Steroids
|
pubmed:year |
2000
|
pubmed:articleTitle |
Bioactive steroids from the whole herb of Euphorbia chamaesyce.
|
pubmed:affiliation |
Department of Medicinal Chemistry, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan. tanakar@oysun01.oups.ac.jp
|
pubmed:publicationType |
Journal Article
|