Source:http://linkedlifedata.com/resource/pubmed/id/10646274
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2000-2-8
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pubmed:abstractText |
We describe a method for producing high-resolution chemical patterns on surfaces to control the attachment and growth of cultured neurons. Microcontact printing has been extended to allow the printing of micron-scale protein lines aligned to an underlying pattern of planar microelectrodes. Poly-L-lysine (PL) lines have been printed on the electrode array for electrical studies on cultured neural networks. Rat hippocampal neurons showed a high degree of attachment selectivity to the PL and produced neurites that faithfully grew onto the electrode recording sites.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0018-9294
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
17-21
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:10646274-Animals,
pubmed-meshheading:10646274-Cell Adhesion,
pubmed-meshheading:10646274-Cell Culture Techniques,
pubmed-meshheading:10646274-Cell Division,
pubmed-meshheading:10646274-Hippocampus,
pubmed-meshheading:10646274-Microelectrodes,
pubmed-meshheading:10646274-Neural Conduction,
pubmed-meshheading:10646274-Neurons,
pubmed-meshheading:10646274-Polylysine,
pubmed-meshheading:10646274-Rats,
pubmed-meshheading:10646274-Surface Properties
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pubmed:year |
2000
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pubmed:articleTitle |
Aligned microcontact printing of micrometer-scale poly-L-lysine structures for controlled growth of cultured neurons on planar microelectrode arrays.
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pubmed:affiliation |
School of Applied and Engineering Physics, Cornell University, Ithaca, NY 14853, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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