Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1976-8-2
pubmed:abstractText
Serum stimulates the production of prostaglandins by transformed mouse fibroblasts. Hydrocortisone (cortisol) inhibits this stimulation. The half-maximal inhibition occurs at 6x10-9 M. Studies with cells labeled with [3H]arachidonic acid in their lipids show that the stimulation by serum results in the release of arachidonic acid from the cellular lipids, mostly phospholipids. Hydrocortisone inhibits this release but does not inhibit the production of prostaglandins from exogenously supplied arachidonic acid. This inhibition of arachidonic acid release from phospholipids may be the mechanism for the anti-inflammatory action of corticosteroids.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-11344573, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-1246330, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-1249205, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-14087609, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-4357612, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-4438348, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-4561329, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-4569497, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-4590022, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-4625237, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-4629972, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-4748510, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-4816891, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-4856884, http://linkedlifedata.com/resource/pubmed/commentcorrection/1064045-5480852
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1735-9
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Kinetics of glucagon in man: effects of starvation.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.