rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2000-2-23
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pubmed:abstractText |
Interleukin-6 (IL-6) is a pleiotropic cytokine that regulates growth and differentiation of various types of malignant tumors, including prostate carcinomas. The levels of IL-6 are elevated in sera of patients with metastatic prostate cancer. In this study, we evaluate the role of IL-6 in the growth regulation of prostate cancer cells.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokine Receptor gp130,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/IL6ST protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/STAT3 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/STAT3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0270-4137
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2000 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
239-42
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10639195-Antigens, CD,
pubmed-meshheading:10639195-Cell Division,
pubmed-meshheading:10639195-Cytokine Receptor gp130,
pubmed-meshheading:10639195-DNA-Binding Proteins,
pubmed-meshheading:10639195-Humans,
pubmed-meshheading:10639195-Interleukin-6,
pubmed-meshheading:10639195-Male,
pubmed-meshheading:10639195-Membrane Glycoproteins,
pubmed-meshheading:10639195-Prostatic Neoplasms,
pubmed-meshheading:10639195-Receptors, Interleukin-6,
pubmed-meshheading:10639195-STAT3 Transcription Factor,
pubmed-meshheading:10639195-Signal Transduction,
pubmed-meshheading:10639195-Trans-Activators,
pubmed-meshheading:10639195-Tumor Cells, Cultured
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pubmed:year |
2000
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pubmed:articleTitle |
Interleukin-6 induces prostate cancer cell growth accompanied by activation of stat3 signaling pathway .
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pubmed:affiliation |
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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