Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2000-2-11
pubmed:abstractText
phenylanthraquinone knipholone (1) and three of its natural derivatives as well as seven structurally related but simplified compounds have been examined for their antiplasmodial activity against asexual erythrocytic stages of two strains of Plasmodium falciparum in vitro (K1/chloroquine-resistant and NF 54/chloroquine-sensitive). All the phenylanthraquinones showed considerable activity with only little cytotoxicity, while their anthraquinone and phenyl moieties were completely inactive. Knipholone (1) and its natural derivatives can therefore be considered as a new group of potential antimalarials
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0032-0943
pubmed:author
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
757-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Antiplasmodial activity of knipholone and related natural phenylanthraquinones.
pubmed:publicationType
Letter, Research Support, Non-U.S. Gov't