Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1976-6-2
pubmed:abstractText
Our observations on the response of TPP+ uptake into K+-depleted cells on the extracellular K+ concentration and on the addition of ouabain and amino acid appear to provide suggestive evidence of, or are at least consistent with, the operation of a powerful, K+-activated electrogenic pump. They are also consistent with the assumption that in these K+-depleted cells the active uptake of amino acid energized by the electric PD presumably generated by this electrogenic pump. It follows that an energy source other than the electrochemical potential gradient of Na+ ions need not be invoked to explain active amino acid transport with inverted Na+ and K+ distribution. In the presence of an electrogenic cation pump one should expect that owing to the activity of this pump the electrical PD is raised under these conditions to a value outweighing the opposed chemical potential gradient of Na+. The experimental evidence so far available is clearly consistent with such an assumption.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0077-8923
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
264
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
428-41
pubmed:dateRevised
2009-10-27
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Driving forces of amino acid transport in animal cells.
pubmed:publicationType
Journal Article