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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1976-6-2
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pubmed:abstractText |
The value of sialochemistry in the study of Sjögren's syndrome was explored by comparative examination of a spectrum of parotid components in twelve subjects with a positive diagnosis of the disease and twelve control subjects with normal gland function. The subjects with Sjögren's syndrome all exhibited a marked reduction in flow rate and phosphate concentration and a marked elevation in sodium and chloride concentration. The concentration of IgA was somewhat elevated (commensurate with reduced flow rate); the levels of IgG, IgM, and albumin were normal. The major functional abnormality in the parotid gland in Sjögren's syndrome appears to be luminal transport in the ductal region; leakage of serum components is minimal. Sialochemistry can be helpful in differentiating Sjögren's disease from other diseases of the salivary gland and in assessing degree of pathologic change.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0030-4220
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
182-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1062746-Adult,
pubmed-meshheading:1062746-Aged,
pubmed-meshheading:1062746-Chlorides,
pubmed-meshheading:1062746-Female,
pubmed-meshheading:1062746-Humans,
pubmed-meshheading:1062746-Immunoglobulins,
pubmed-meshheading:1062746-Middle Aged,
pubmed-meshheading:1062746-Potassium,
pubmed-meshheading:1062746-Saliva,
pubmed-meshheading:1062746-Sjogren's Syndrome,
pubmed-meshheading:1062746-Sodium
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pubmed:year |
1976
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pubmed:articleTitle |
Sialochemistry in Sjögren's syndrome.
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pubmed:publicationType |
Journal Article
|