|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0004613,
umls-concept:C0007090,
umls-concept:C0021853,
umls-concept:C0041213,
umls-concept:C0086418,
umls-concept:C0205309,
umls-concept:C0301630,
umls-concept:C1555707,
umls-concept:C1705851,
umls-concept:C2752151,
umls-concept:C2828366
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|
pubmed:issue |
2-3
|
|
pubmed:dateCreated |
1979-5-16
|
|
pubmed:abstractText |
The azo reductase activity of a cell-free extract of Fusobacterium sp. 2 is characterized using trypan blue as a substrate. Either chemical reduction of this dye with sodium hydrosulfite or reduction by the cell-free extract produces a mutagenic product, o-tolidine. The o-tolidine is mutagenic in the Ames Salmonella/mammalian-microsome mutagenicity test when activated by a rat liver S9 preparation.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0027-5107
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
58
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
125-32
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:106267-Benzidines,
pubmed-meshheading:106267-Carcinogens,
pubmed-meshheading:106267-Fusobacterium,
pubmed-meshheading:106267-Genetic Techniques,
pubmed-meshheading:106267-Humans,
pubmed-meshheading:106267-Intestines,
pubmed-meshheading:106267-Mutagens,
pubmed-meshheading:106267-NADH, NADPH Oxidoreductases,
pubmed-meshheading:106267-Trypan Blue,
pubmed-meshheading:106267-p-Dimethylaminoazobenzene
|
|
pubmed:year |
1978
|
|
pubmed:articleTitle |
Azo reduction of trypan blue to a known carcinogen by a cell-free extract of a human intestinal anaerobe.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
