10623704

Source:http://linkedlifedata.com/resource/pubmed/id/10623704

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0008976, umls-concept:C0034656, umls-concept:C0036525, umls-concept:C0069717, umls-concept:C0205390, umls-concept:C1522484, umls-concept:C1524062, umls-concept:C1527249, umls-concept:C1708063
pubmed:issue	1
pubmed:dateCreated	2000-2-17
pubmed:abstractText	To study how adding oxaliplatin (l-OHP) to chronomodulated fluorouracil (5-FU)-leucovorin (LV) affected the objective response rate, as first-line treatment of metastatic colorectal cancer.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8309333
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Fluorouracil, http://linkedlifedata.com/resource/pubmed/chemical/Leucovorin, http://linkedlifedata.com/resource/pubmed/chemical/Organoplatinum Compounds, http://linkedlifedata.com/resource/pubmed/chemical/oxaliplatin
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	0732-183X
pubmed:author	pubmed-author:AdamRR, pubmed-author:Bertheaut-CvitkovicFF, pubmed-author:CholletPP, pubmed-author:CoudertBB, pubmed-author:FaggiuoloRR, pubmed-author:FocanCC, pubmed-author:GiacchettiSS, pubmed-author:LéviFF, pubmed-author:Larregain-FournierDD, pubmed-author:Le BailNN, pubmed-author:Le RolAA, pubmed-author:LetourneauYY, pubmed-author:LlortJ MJM, pubmed-author:MissetJ LJL, pubmed-author:PerpointBB, pubmed-author:WalterSS, pubmed-author:ZidaniRR
pubmed:issnType	Print
pubmed:volume	18
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	136-47
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:10623704-Adult, pubmed-meshheading:10623704-Aged, pubmed-meshheading:10623704-Analysis of Variance, pubmed-meshheading:10623704-Antineoplastic Combined Chemotherapy Protocols, pubmed-meshheading:10623704-Chronotherapy, pubmed-meshheading:10623704-Colorectal Neoplasms, pubmed-meshheading:10623704-Disease-Free Survival, pubmed-meshheading:10623704-Dose-Response Relationship, Drug, pubmed-meshheading:10623704-Europe, pubmed-meshheading:10623704-Female, pubmed-meshheading:10623704-Fluorouracil, pubmed-meshheading:10623704-Humans, pubmed-meshheading:10623704-Leucovorin, pubmed-meshheading:10623704-Logistic Models, pubmed-meshheading:10623704-Male, pubmed-meshheading:10623704-Middle Aged, pubmed-meshheading:10623704-Organoplatinum Compounds, pubmed-meshheading:10623704-Survival Rate
pubmed:year	2000
pubmed:articleTitle	Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer.
pubmed:affiliation	International Organization of Cancer Chronotherapy, Centre de Chronothérapie, Hôpital Paul Brousse, Villejuif, France. sylvie.giacchetti@pbr.ab-hop-paris.fr
pubmed:publicationType	Journal Article, Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Multicenter Study, Clinical Trial, Phase III