Linked Life Data

10622643

Source:http://linkedlifedata.com/resource/pubmed/id/10622643

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2000-2-22
pubmed:abstractText
Microsporidia are obligate intracellular, spore-forming protozoa and are regarded as newly emerging pathogens . Enterocytozoon spp. as well as Encephalitozoon spp. are recognized as major aetiological agents in chronic diarrhoea of immnunocompromised patients. The detection and differentiation of strains within microsporidial species is a prerequisite for the elucidation of their hitherto unknown reservoirs and their mode of transmission . In Enterocytozoon bieneusi, the most prevalent human-pathogenic microsporidium, 6 different genotypes of the internal transcribed spacer (ITS) of the rRNA gene are known so far, with 12 polymorphic sites . This pathogen has infrequently been detected in 2 animal hosts only, pigs and rhesus macaques, and only the genotype of the latter has also been found in a human patient, too. Encephalitozoon cuniculi has a wider confirmed spectrum of animal hosts, but only one polymorphic site is known in the ITS, differing in 3 different numbers of a tetranucleotide repeat. Therefore, further genomic targets may have to be characterized, too. Few data are available on strain differentiation in Encephalitozoon intestinalis and E. hellem.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0385-0005
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
433-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Strain differentiation in microsporidia.
pubmed:affiliation
Department of Infectious Diseases and Tropical Medicine, Klinikum Innenstadt, University of Munich, Germany.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't