Linked Life Data

10619413

Source:http://linkedlifedata.com/resource/pubmed/id/10619413

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-1-20
pubmed:abstractText
For the study of functional organization and reorganization of the human cortex by means of electromagnetic source imaging, a measure of the location and spatial extent of neural sources is of interest. This study evaluates the cortical patch method (CPM), an iterative procedure introduced by Lütkenhöner et al. [1995] that models EEG/MEG activity by means of extended cortical patches. Anatomical information is used to constrain estimates of location and extent of neural sources that generate the measured evoked potential. Whereas minimum norm approaches use mathematical constraints to solve the ambiguity of the inverse problem, the CPM introduces constraints based on anatomical and physiological knowledge about neural mass activity. In order to test the proposed method, the simulated activity in an artificial sulcus was subjected to the CPM. The results show that even activity on opposing walls of a sulcus can be well reconstructed. The simulations demonstrate the usefulness and limits of the CPM in estimating the spatial extent of neural sources in the cerebral cortex. As an example, an application of the method on experimental somatosensory evoked potentials is presented in the Appendix.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1065-9471
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
182-93
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Modeling extended sources of event-related potentials using anatomical and physiological constraints.
pubmed:affiliation
Institute of Medical Psychology, University of Tübingen, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't