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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2000-2-24
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pubmed:abstractText |
A common 4G allele of a 4G/5G polymorphism in the promoter region of the plasminogen activator inhibitor-1 (PAI-1) gene is associated with increased transcription of the PAI-1 protein, which may lead to decreased fibrinolysis. It has therefore been proposed as a candidate risk factor for myocardial infarction or stroke.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0009-7322
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
67-70
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10618306-Age Factors,
pubmed-meshheading:10618306-Aged,
pubmed-meshheading:10618306-Cardiovascular Diseases,
pubmed-meshheading:10618306-Cerebrovascular Disorders,
pubmed-meshheading:10618306-Cohort Studies,
pubmed-meshheading:10618306-DNA,
pubmed-meshheading:10618306-Female,
pubmed-meshheading:10618306-Follow-Up Studies,
pubmed-meshheading:10618306-Genotype,
pubmed-meshheading:10618306-Humans,
pubmed-meshheading:10618306-Longitudinal Studies,
pubmed-meshheading:10618306-Middle Aged,
pubmed-meshheading:10618306-Myocardial Infarction,
pubmed-meshheading:10618306-Plasminogen Activator Inhibitor 1,
pubmed-meshheading:10618306-Polymorphism, Genetic,
pubmed-meshheading:10618306-Postmenopause,
pubmed-meshheading:10618306-Promoter Regions, Genetic,
pubmed-meshheading:10618306-Risk Factors,
pubmed-meshheading:10618306-Time Factors
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pubmed:articleTitle |
Plasminogen activator inhibitor 4G polymorphism is associated with decreased risk of cerebrovascular mortality in older women.
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pubmed:affiliation |
Julius Center for Patient Oriented Research, Department of Hematology, Graduate School of Biomembranes, Utrecht University Medical School, Netherlands. M.Roest@jc.azu.nl
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pubmed:publicationType |
Journal Article
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