Linked Life Data

10617166

Source:http://linkedlifedata.com/resource/pubmed/id/10617166

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2000-2-1
pubmed:abstractText
Increasing respiratory effort is the likely stimulus for arousal in patients with sleep-disordered breathing. Changes in the phase angle waveform (an indirect measure of respiratory effort) may provide a useful non-EEG indicator of respiratory-related arousal. The aim of this study was to investigate the relationship between phase angle change (using a continuous measurement technique) and EEG arousal. Polysomnographic sleep recordings (including: EEG, EOG, EMG, respiratory effort [ribcage and abdominal movement], respiratory paradox [continuous phase angle measurement], oral-nasal airflow, and oxygen saturation) were performed in a purpose built laboratory on 30 patients with sleep-disordered breathing (15 patients with obstructive sleep apnoea/hypopnoea syndrome [OSAHS]; 15 chronic heavy snorers without OSAHS) and 15 age and weight matched, non-snoring normal subjects. All data, including the temporal relationship between phase angle change and EEG arousal, were analyzed manually (4,545 phase angle changes and 6,473 EEG arousals). There was a highly significant correlation (p<0.001) between phase angle index (changes/hour of sleep) and EEG arousal index (arousals/hour of sleep). However, mean phase angle index allowed a much clearer differentiation between the three subject groups, with the mean phase angle index providing a six-fold difference between normal and OSAHS groups, while the EEG arousal index gave only a two-fold difference. In support of the suggestion that phase angle changes represent respiratory-related sleep disruption, more than twice as many EEG arousals were associated with a change in the phase angle waveform in patients with sleep-disordered breathing than in normal subjects. This study highlights the limitations of EEG arousal scoring in the assessment of patients with sleep-disordered breathing and provides further evidence to support phase angle change as an indicator of respiratory-related sleep disruption.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0161-8105
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1059-65
pubmed:dateRevised
2009-1-29
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Respiratory paradox as an indicator of arousal from non-REM sleep.
pubmed:affiliation
North West Lung Centre, Wythenshawe Hospital, Manchester, UK.
pubmed:publicationType
Journal Article, Comparative Study