Source:http://linkedlifedata.com/resource/pubmed/id/10616728
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
2000-2-14
|
| pubmed:abstractText |
A series of 2',3'-dideoxy-2'-fluoro-L-threo-pentofuranosyl nucleosides has been synthesized as potential antiviral agents. The synthesized compounds were evaluated against HIV-1, HBV, HSV-1, and HSV-2. Among the synthesized analogues, only the cytosine derivative showed moderate antiviral activity against HIV and HBV.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0732-8311
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
18
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
2233-52
|
| pubmed:dateRevised |
2007-11-14
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| pubmed:meshHeading |
pubmed-meshheading:10616728-Antiviral Agents,
pubmed-meshheading:10616728-HIV-1,
pubmed-meshheading:10616728-Hepatitis B virus,
pubmed-meshheading:10616728-Nucleosides,
pubmed-meshheading:10616728-Simplexvirus,
pubmed-meshheading:10616728-Stereoisomerism,
pubmed-meshheading:10616728-Structure-Activity Relationship,
pubmed-meshheading:10616728-Virus Replication
|
| pubmed:year |
1999
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| pubmed:articleTitle |
Synthesis of 2',3'-dideoxy-2'-fluoro-L-threo-pentofuranosyl nucleosides as potential antiviral agents.
|
| pubmed:affiliation |
Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens 30602, USA.
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| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|