Source:http://linkedlifedata.com/resource/pubmed/id/10616279
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1-2
|
| pubmed:dateCreated |
2000-2-3
|
| pubmed:abstractText |
We analyze an epidemiological model consisting of a linear chain of three cocirculating influenza A strains that provide hosts exposed to a given strain with partial immune cross-protection against other strains. In the extreme case where infection with the middle strain prevents further infections from the other two strains, we reduce the model to a six-dimensional kernel capable of showing self-sustaining oscillations at relatively high levels of cross-protection. Dimensional reduction has been accomplished by a transformation of variables that preserves the eigenvalue responsible for the transition from damped oscillations to limit cycle solutions.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0025-5564
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
162
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
33-51
|
| pubmed:dateRevised |
2009-11-11
|
| pubmed:meshHeading |
pubmed-meshheading:10616279-Antigenic Variation,
pubmed-meshheading:10616279-Gene Frequency,
pubmed-meshheading:10616279-Humans,
pubmed-meshheading:10616279-Influenza, Human,
pubmed-meshheading:10616279-Influenza A virus,
pubmed-meshheading:10616279-Linear Models,
pubmed-meshheading:10616279-Models, Biological,
pubmed-meshheading:10616279-Point Mutation
|
| pubmed:articleTitle |
Dynamics of influenza A drift: the linear three-strain model.
|
| pubmed:affiliation |
Department of Physics, Washington College, Chestertown, MD 21620, USA. juan.lin@washcoll.edu
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|