| pubmed-article:10615998 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10615998 | lifeskim:mentions | umls-concept:C0017296 | lld:lifeskim |
| pubmed-article:10615998 | lifeskim:mentions | umls-concept:C0040669 | lld:lifeskim |
| pubmed-article:10615998 | lifeskim:mentions | umls-concept:C0521447 | lld:lifeskim |
| pubmed-article:10615998 | lifeskim:mentions | umls-concept:C0028948 | lld:lifeskim |
| pubmed-article:10615998 | lifeskim:mentions | umls-concept:C0439793 | lld:lifeskim |
| pubmed-article:10615998 | lifeskim:mentions | umls-concept:C0971858 | lld:lifeskim |
| pubmed-article:10615998 | lifeskim:mentions | umls-concept:C0079429 | lld:lifeskim |
| pubmed-article:10615998 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:10615998 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:10615998 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:10615998 | pubmed:dateCreated | 2000-1-28 | lld:pubmed |
| pubmed-article:10615998 | pubmed:abstractText | In both rheumatoid arthritis and collagen-induced arthritis (CIA), the nuclear factor kappaB (NF-kappaB) transcription factor plays a pivotal role in the coordinated transactivation of many cytokines related to pathogenesis. This study investigated whether synthetic double-stranded DNA that show a high affinity for NF-kappaB could be introduced in vivo as "decoy" cis elements to bind the transcription factor and block the activation of such proinflammatory cytokine genes as interleukin-1 (IL-1) and tumor necrosis factor alpha (TNFalpha), and thus suppress the severity of joint destruction. | lld:pubmed |
| pubmed-article:10615998 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10615998 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10615998 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:10615998 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:10615998 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10615998 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10615998 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:10615998 | pubmed:issn | 0004-3591 | lld:pubmed |
| pubmed-article:10615998 | pubmed:author | pubmed-author:KatoKK | lld:pubmed |
| pubmed-article:10615998 | pubmed:author | pubmed-author:SekiHH | lld:pubmed |
| pubmed-article:10615998 | pubmed:author | pubmed-author:TomitaTT | lld:pubmed |
| pubmed-article:10615998 | pubmed:author | pubmed-author:YamamotoKK | lld:pubmed |
| pubmed-article:10615998 | pubmed:author | pubmed-author:KanekoMM | lld:pubmed |
| pubmed-article:10615998 | pubmed:author | pubmed-author:MorishitaRR | lld:pubmed |
| pubmed-article:10615998 | pubmed:author | pubmed-author:OchiTT | lld:pubmed |
| pubmed-article:10615998 | pubmed:author | pubmed-author:KanedaYY | lld:pubmed |
| pubmed-article:10615998 | pubmed:author | pubmed-author:TakeuchiEE | lld:pubmed |
| pubmed-article:10615998 | pubmed:author | pubmed-author:TomitaNN | lld:pubmed |
| pubmed-article:10615998 | pubmed:author | pubmed-author:NakaseTT | lld:pubmed |
| pubmed-article:10615998 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10615998 | pubmed:volume | 42 | lld:pubmed |
| pubmed-article:10615998 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10615998 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10615998 | pubmed:pagination | 2532-42 | lld:pubmed |
| pubmed-article:10615998 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:10615998 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10615998 | pubmed:articleTitle | Suppressed severity of collagen-induced arthritis by in vivo transfection of nuclear factor kappaB decoy oligodeoxynucleotides as a gene therapy. | lld:pubmed |
| pubmed-article:10615998 | pubmed:affiliation | Department of Orthopaedic Surgery, Osaka University Medical School, Suita, Japan. | lld:pubmed |
| pubmed-article:10615998 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10615998 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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