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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2000-1-14
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pubmed:abstractText |
The glycoprotein P-selectin is an adhesion molecule that is rapidly expressed on the surface of platelets and endothelium during the inflammatory process. P-selectin on endothelium has been reported to play an important role in reperfusion injury. However, little is known regarding P-selectin on platelets in contributing to the pathophysiology of myocardial reperfusion injury. In this study, we hypothesized that P-selectin on platelets may enhance neutrophil endothelial adherence and this may play a role in neutrophil-mediated reperfusion injury.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
968-73
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10615424-Animals,
pubmed-meshheading:10615424-Antibodies, Monoclonal,
pubmed-meshheading:10615424-Blood Platelets,
pubmed-meshheading:10615424-Cell Adhesion,
pubmed-meshheading:10615424-Cell Movement,
pubmed-meshheading:10615424-Cells, Cultured,
pubmed-meshheading:10615424-Coculture Techniques,
pubmed-meshheading:10615424-Endothelium, Vascular,
pubmed-meshheading:10615424-Male,
pubmed-meshheading:10615424-Mice,
pubmed-meshheading:10615424-Myocardial Reperfusion Injury,
pubmed-meshheading:10615424-Myocardium,
pubmed-meshheading:10615424-Neutrophils,
pubmed-meshheading:10615424-P-Selectin,
pubmed-meshheading:10615424-Platelet Activation,
pubmed-meshheading:10615424-Rats,
pubmed-meshheading:10615424-Rats, Sprague-Dawley
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pubmed:year |
1999
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pubmed:articleTitle |
Selectin on activated platelets enhances neutrophil endothelial adherence in myocardial reperfusion injury.
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pubmed:affiliation |
Department of Pediatrics, Faculty of Medicine, Osaka University, Japan.
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pubmed:publicationType |
Journal Article
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