Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5450
pubmed:dateCreated
2000-1-20
pubmed:abstractText
Dorsal and ventral aspects of the eye are distinct from the early stages of development. The developing eye cup grows dorsally, and the choroidal fissure is formed on its ventral side. Retinal axons from the dorsal and ventral retina project to the ventral and dorsal tectum, respectively. Misexpression of the Tbx5 gene induced dorsalization of the ventral side of the eye and altered projections of retinal ganglion cell axons. Thus, Tbx5 is involved in eye morphogenesis and is a topographic determinant of the visual projections between retina and tectum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Avian Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Bone Morphogenetic Protein 4, http://linkedlifedata.com/resource/pubmed/chemical/Bone Morphogenetic Proteins, http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Ephrin-B1, http://linkedlifedata.com/resource/pubmed/chemical/Ephrin-B2, http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins, http://linkedlifedata.com/resource/pubmed/chemical/PAX2 Transcription Factor, http://linkedlifedata.com/resource/pubmed/chemical/T-Box Domain Proteins, http://linkedlifedata.com/resource/pubmed/chemical/T-box transcription factor 5, http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors, http://linkedlifedata.com/resource/pubmed/chemical/Vax protein, chicken
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
287
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
134-7
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:10615048-Animals, pubmed-meshheading:10615048-Avian Proteins, pubmed-meshheading:10615048-Axons, pubmed-meshheading:10615048-Body Patterning, pubmed-meshheading:10615048-Bone Morphogenetic Protein 4, pubmed-meshheading:10615048-Bone Morphogenetic Proteins, pubmed-meshheading:10615048-Chick Embryo, pubmed-meshheading:10615048-DNA-Binding Proteins, pubmed-meshheading:10615048-Electroporation, pubmed-meshheading:10615048-Ephrin-B1, pubmed-meshheading:10615048-Ephrin-B2, pubmed-meshheading:10615048-Eye, pubmed-meshheading:10615048-Gene Expression, pubmed-meshheading:10615048-Homeodomain Proteins, pubmed-meshheading:10615048-Membrane Proteins, pubmed-meshheading:10615048-Morphogenesis, pubmed-meshheading:10615048-PAX2 Transcription Factor, pubmed-meshheading:10615048-Pigment Epithelium of Eye, pubmed-meshheading:10615048-Retina, pubmed-meshheading:10615048-Retinal Ganglion Cells, pubmed-meshheading:10615048-Superior Colliculi, pubmed-meshheading:10615048-T-Box Domain Proteins, pubmed-meshheading:10615048-Transcription Factors, pubmed-meshheading:10615048-Transfection, pubmed-meshheading:10615048-Transgenes
pubmed:year
2000
pubmed:articleTitle
Tbx5 and the retinotectum projection.
pubmed:affiliation
Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5, Takayama, Ikoma, Nara, Japan 630-0101.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't