Linked Life Data

10612915

Source:http://linkedlifedata.com/resource/pubmed/id/10612915

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2000-3-7
pubmed:abstractText
This study evaluated the effect of titanium endosseous dental implants coupled to dissimilar materials on the capacity of preosteoblasts in bone marrow culture to differentiate, to form alkaline phosphatase-positive colonies, and to mineralize. Ten UCLA abutments were cast in each of 4 alloys: Type III gold, ceramometal gold, commercially pure grade I titanium, and titanium-aluminum-vanadium (Ti-6Al-4V); 10 ceramic abutments and 30 sterile Brånemark System implants were also used. Five abutments of each material and 5 implants were incubated individually in rat bone marrow culture, as were 5 of each abutment attached to an implant; bone marrow cultures not containing test samples were used as controls. Following 17 days of culture, the solution potentials of individual abutments (except ceramic), the implant, and the implant-abutment couples were measured in the test medium. One dish of each group of 5 was then stained for bone nodule mineralization; the remainder were quantified by area for alkaline phosphatase staining. Statistical analysis of measured in vitro potentials showed that the uncoupled samples formed 2 groups, and coupled samples formed 3 groups. Analysis of variance for alkaline phosphatase-positive area values showed no significant differences between coupled or uncoupled groups and the control. Normal cell differentiation and morphology as well as a lack of zones of inhibition, were observed. Bone nodule mineralization was evident in all groups. It was concluded that the presence of these commonly used implant abutment biomaterials coupled to titanium endosseous dental implants had no adverse effects on the in vitro capacity of preosteoblasts in marrow to differentiate and to form mineralized bone nodules, despite measured differences in solution potentials.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0882-2786
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
785-97
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
The effects of the coupling of titanium implants and dissimilar metal abutments on osteoblast differentiation in vitro.
pubmed:affiliation
Division of Prosthodontics, Faculty of Dentistry, Dalhousie University, Halifax, Nova Scotia, Canada. jctaylor@istar.ca
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't