10612602

Source:http://linkedlifedata.com/resource/pubmed/id/10612602

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0034801, umls-concept:C0220781, umls-concept:C0597358, umls-concept:C0871161, umls-concept:C1883254
pubmed:issue	23
pubmed:dateCreated	2000-1-13
pubmed:abstractText	A class of opioid receptor active derivatives of oxymorphone has been synthesized using a common enaminone intermediate. The derivatives have heterocyclic groups fused to the 6,7-positions of the morphinan system and all were synthesized in high yield. A pyrazolo derivative is an agonist for the mu and delta receptors and an antagonist for the kappa receptor.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/KO2-DA-00130
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Morphinans, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Opioid
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	0960-894X
pubmed:author	pubmed-author:BauerLL, pubmed-author:BhargavaH NHN, pubmed-author:DunnW JWJ3rd, pubmed-author:HuangL FLF, pubmed-author:XuWW
pubmed:issnType	Print
pubmed:day	6
pubmed:volume	9
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	3375-80
pubmed:dateRevised	2007-11-14
pubmed:meshHeading	pubmed-meshheading:10612602-Morphinans, pubmed-meshheading:10612602-Receptors, Opioid, pubmed-meshheading:10612602-Structure-Activity Relationship
pubmed:year	1999
pubmed:articleTitle	Synthesis and opiate receptor binding properties of 17-methyl-6,7-dehydro-3,14-dihydroxy-4,5alpha-epoxy-6,7:4',5'-pyrimidin omorphinans.
pubmed:affiliation	College of Pharmacy, University of Illinois at Chicago, 60612-7231, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S.