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pubmed-article:10612601pubmed:abstractTextA series of 4-hydroxy-1-[3-(5-(1,2,4-triazol-4-yl)-1H-indol-3-yl)propyl] piperidines was investigated as potential selective h5-HT1D agonists for the treatment of migraine. The 4-[(N-benzyl-N-methyl)amino]methyl analog 12a was found to be a full agonist at the h5-HT1D receptor with good binding selectivity over the h5-HT1B receptor.lld:pubmed
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pubmed-article:10612601pubmed:affiliationMerck, Sharp & Dohme Research Laboratories, Terlings Park, Harlow, UK. Sylvie Bourrain@Merck.comlld:pubmed
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