Linked Life Data

1061027

Source:http://linkedlifedata.com/resource/pubmed/id/1061027

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1976-3-30
pubmed:abstractText
The present investigation has shown that in chemical carcinogenesis progression of malignant epithelial changes in associated with an increased number of cells with chromosomal deviations. Each out of two oncogenic agents with different chemical characteristics had its own non-random pattern. There was usually a close relationship between such chromosomal changes and the simultaneous presence of morphological atypia (dysplasia) and metabolic atypia (aberrant G-6-P.DH activity) from moderate dysplasia and onwards during carcinogenesis. Changes in X-chromosomes, which i.a. in human code the synthesis of G-6-P.DH molecules, could perhaps explain and be reflected in deviating metabolic reactions in premalignant cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0029-8441
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
309-26
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1975
pubmed:articleTitle
Cytogenetic and histochemical analysis of experimental oral carcinogenesis in the rat.
pubmed:publicationType
Journal Article