Linked Life Data

10609996

Source:http://linkedlifedata.com/resource/pubmed/id/10609996

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2000-1-7
pubmed:abstractText
This paper describes and tests the LL-EPI method for obtaining quantitative T1 estimates in a few seconds thereby allowing dynamic T1 studies. It is shown that the method works even when there is an inflow into the imaged volume, e.g., in a vessel. No calibration is needed. The method has been tested in a phantom study with several different scan parameter set-ups, with and without inflow. The method shows robustness and individual scan parameters and inflow rates do not influence the ability to calculate the Gd-DTPA concentration. Linearity prevail between the measured 1/T1 and the Gd-DTPA concentration in the range 150 < T1 < 2500 ms. In a dynamic Gd-DTPA phantom study, it was shown that the dynamic LL-EPI T1 mapping technique was three times more sensitive than the signal from a T2*-weighted EPI sequence. In an in vivo study, dynamic T1 mapping of the Gd-DTPA uptake in a meningioma was performed. Inspection of the uptake curves indicates that the method is feasible in clinical perfusion studies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0730-725X
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1481-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Phantom and in vivo study of the Look-Locher T1 mapping method.
pubmed:affiliation
MR Research Center, Karolinska Institute, Stockholm, Sweden. magnus@mrc.ks.se
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't