Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2000-1-5
pubmed:abstractText
Aldosterone synthase (CYP11B2) is a key enzyme in the biosynthesis of aldosterone. Recently, the T allele of a polymorphism in the 5'-flanking region of the CYP11B2 gene (C-344T) has been reported to be more frequent in hypertensives than in normotensives, and has also been associated with increased plasma aldosterone levels. We therefore hypothesized that this variant may be related to increased blood-pressure response to dietary salt intake.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0263-6352
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1563-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:10608469-Adult, pubmed-meshheading:10608469-Aldosterone, pubmed-meshheading:10608469-Aldosterone Synthase, pubmed-meshheading:10608469-Alleles, pubmed-meshheading:10608469-Angiotensinogen, pubmed-meshheading:10608469-Anthropometry, pubmed-meshheading:10608469-Blood Pressure, pubmed-meshheading:10608469-Cross-Over Studies, pubmed-meshheading:10608469-Diet, Sodium-Restricted, pubmed-meshheading:10608469-Drug Resistance, pubmed-meshheading:10608469-European Continental Ancestry Group, pubmed-meshheading:10608469-Gene Frequency, pubmed-meshheading:10608469-Genotype, pubmed-meshheading:10608469-Humans, pubmed-meshheading:10608469-Hypertension, pubmed-meshheading:10608469-Male, pubmed-meshheading:10608469-Polymorphism, Genetic, pubmed-meshheading:10608469-Renin, pubmed-meshheading:10608469-Single-Blind Method, pubmed-meshheading:10608469-Sodium Chloride
pubmed:year
1999
pubmed:articleTitle
Aldosterone synthase gene (CYP11B2) C-344T polymorphism in Caucasians from the Berlin Salt-Sensitivity Trial (BeSST).
pubmed:affiliation
Department of Internal Medicine, Universitätsklinkum Benjamin Franklin, Freie Universität Berlin, Germany.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial, Research Support, Non-U.S. Gov't