rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2000-2-24
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pubmed:abstractText |
The effects of hypoxia on renin secretion and renin gene expression have been controversial. In recent studies, we have demonstrated that acute hypoxia of 6 h duration caused a marked stimulation of renin secretion and renal renin gene expression. This hypoxia-induced stimulation of the renin-angiotensin system might contribute, for example, to the progression of chronic renal failure and to the development of hypertension in the sleep-apnoea syndrome. For this reason, we were interested in the more chronic effects of hypoxia on renal renin gene expression and its possible regulation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Endothelin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Endothelin-3,
http://linkedlifedata.com/resource/pubmed/chemical/LU 135252,
http://linkedlifedata.com/resource/pubmed/chemical/Molsidomine,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Donors,
http://linkedlifedata.com/resource/pubmed/chemical/Phenylpropionates,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrimidines,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Endothelin,
http://linkedlifedata.com/resource/pubmed/chemical/Renin
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0931-0509
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
11-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10607761-Animals,
pubmed-meshheading:10607761-Anoxia,
pubmed-meshheading:10607761-Blood Pressure,
pubmed-meshheading:10607761-Chronic Disease,
pubmed-meshheading:10607761-Endothelin-1,
pubmed-meshheading:10607761-Endothelin-3,
pubmed-meshheading:10607761-Gene Expression,
pubmed-meshheading:10607761-Kidney,
pubmed-meshheading:10607761-Male,
pubmed-meshheading:10607761-Molsidomine,
pubmed-meshheading:10607761-Nitric Oxide Donors,
pubmed-meshheading:10607761-Phenylpropionates,
pubmed-meshheading:10607761-Pyrimidines,
pubmed-meshheading:10607761-RNA, Messenger,
pubmed-meshheading:10607761-Rats,
pubmed-meshheading:10607761-Rats, Wistar,
pubmed-meshheading:10607761-Receptors, Endothelin,
pubmed-meshheading:10607761-Renin
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pubmed:year |
2000
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pubmed:articleTitle |
Effects of chronic hypoxia on renal renin gene expression in rats.
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pubmed:affiliation |
Klinik und Poliklinik für Innere Medizin II, Klinikum der Universität Regensburg, Regensburg, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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