10607584

Source:http://linkedlifedata.com/resource/pubmed/id/10607584

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C1335193, umls-concept:C1521761
pubmed:issue	24
pubmed:dateCreated	2000-2-16
pubmed:abstractText	Recent studies have identified the transcription factor Pax5 as a critical determinant of commitment to the B-lymphocyte pathway. Surprisingly, Pax5 appears to achieve this primarily through suppressing alternative haematopoietic lineage fates.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107782
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/B-Cell-Specific Activator Protein, http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins, http://linkedlifedata.com/resource/pubmed/chemical/PAX5 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Pax5 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors
pubmed:status	MEDLINE
pubmed:issn	0960-9822
pubmed:author	pubmed-author:EnverTT
pubmed:issnType	Print
pubmed:volume	9
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	R933-5
pubmed:dateRevised	2005-11-17
pubmed:meshHeading	pubmed-meshheading:10607584-Animals, pubmed-meshheading:10607584-B-Cell-Specific Activator Protein, pubmed-meshheading:10607584-B-Lymphocytes, pubmed-meshheading:10607584-Cell Differentiation, pubmed-meshheading:10607584-DNA-Binding Proteins, pubmed-meshheading:10607584-Hematopoiesis, pubmed-meshheading:10607584-Hematopoietic Stem Cells, pubmed-meshheading:10607584-Humans, pubmed-meshheading:10607584-Mice, pubmed-meshheading:10607584-Mice, Knockout, pubmed-meshheading:10607584-Nuclear Proteins, pubmed-meshheading:10607584-Transcription Factors
pubmed:articleTitle	B-cell commitment: Pax5 is the deciding factor.
pubmed:affiliation	Section of Gene Function and Regulation, Chester Beatty Laboratories, Institute of Cancer Research, London, SW3 6JB, UK. tariq@icr.ac.uk
pubmed:publicationType	Journal Article, Review