Linked Life Data

10601730

Source:http://linkedlifedata.com/resource/pubmed/id/10601730

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2000-2-10
pubmed:abstractText
Hyaluronan is an extracellular polysaccharide found throughout the extracellular matrix, especially in soft connective tissue. It has an unusual feature, in that its turnover rate is much greater than that of other extracellular matrix components. The mechanisms of its synthesis at the plasma membrane (by hyaluronan synthases) and lysosomal degradation (by hyaluronidases) are well documented. However, the mechanisms by which it enters those cells primarily involved in its degradation remain a mystery. Recent work now suggests that a novel scavenger receptor expressed on the surface of liver endothelial cells is responsible for part of this degradative process. Further study is required to fill the remaining gaps in our knowledge about this process in other tissues.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0945-053X
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
427-32
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
How does the hyaluronan scrap-yard operate?
pubmed:affiliation
Department of Experimental Pathology, Institute for Medical Biology, University of Tromsø, Norway. petermcc@fagmed.uit.no
pubmed:publicationType
Journal Article, Review