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pubmed-article:10597774pubmed:abstractTextNef was shown to be the predominant viral protein expressed in HIV-1-infected astrocytes in vivo and in vitro suggesting a distinct role of Nef in this cell type. Nef-induced activation of T cells is well described, whereas the functional activities of Nef in astrocytes are unknown. Our aim was to examine the effect of Nef on growth properties and activation of astrocytes.lld:pubmed
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pubmed-article:10597774pubmed:articleTitleStable expression of HIV-1 Nef induces changes in growth properties and activation state of human astrocytes.lld:pubmed
pubmed-article:10597774pubmed:affiliationGSF-National Research Center for Environment and Health, Institute of Molecular Virology, Neuherberg, Germany.lld:pubmed
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