rdf:type |
|
lifeskim:mentions |
umls-concept:C0004112,
umls-concept:C0017262,
umls-concept:C0018270,
umls-concept:C0019704,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C0205360,
umls-concept:C0392747,
umls-concept:C0443172,
umls-concept:C0871161,
umls-concept:C1442792,
umls-concept:C1879547,
umls-concept:C2911684
|
pubmed:issue |
17
|
pubmed:dateCreated |
2000-1-24
|
pubmed:abstractText |
Nef was shown to be the predominant viral protein expressed in HIV-1-infected astrocytes in vivo and in vitro suggesting a distinct role of Nef in this cell type. Nef-induced activation of T cells is well described, whereas the functional activities of Nef in astrocytes are unknown. Our aim was to examine the effect of Nef on growth properties and activation of astrocytes.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0269-9370
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
3
|
pubmed:volume |
13
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2331-41
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10597774-Apoptosis,
pubmed-meshheading:10597774-Astrocytes,
pubmed-meshheading:10597774-Base Sequence,
pubmed-meshheading:10597774-Cell Division,
pubmed-meshheading:10597774-Cell Line,
pubmed-meshheading:10597774-DNA Primers,
pubmed-meshheading:10597774-Gene Expression,
pubmed-meshheading:10597774-Gene Products, nef,
pubmed-meshheading:10597774-Genes, nef,
pubmed-meshheading:10597774-Glial Fibrillary Acidic Protein,
pubmed-meshheading:10597774-HIV Infections,
pubmed-meshheading:10597774-HIV-1,
pubmed-meshheading:10597774-Humans,
pubmed-meshheading:10597774-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:10597774-T-Lymphocytes,
pubmed-meshheading:10597774-Virulence,
pubmed-meshheading:10597774-nef Gene Products, Human Immunodeficiency Virus
|
pubmed:year |
1999
|
pubmed:articleTitle |
Stable expression of HIV-1 Nef induces changes in growth properties and activation state of human astrocytes.
|
pubmed:affiliation |
GSF-National Research Center for Environment and Health, Institute of Molecular Virology, Neuherberg, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|