Source:http://linkedlifedata.com/resource/pubmed/id/10597507
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2000-1-24
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pubmed:abstractText |
The effect of inclusion of environmental risk factors on the power of sib-pair linkage methods was tested for a qualitative trait. It was found that inclusion of an environmental variable did not increase the power of the Haseman-Elston (H-E) sib-pair nonparametric linkage analysis test. However, a significant increase in power was observed for both the H-E and affected-sib-pair tests, even in small samples, when persons unexposed to the environmental risk factor were coded as unknown.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0741-0395
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S643-8
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:10597507-Environment,
pubmed-meshheading:10597507-Genetic Linkage,
pubmed-meshheading:10597507-Genetic Predisposition to Disease,
pubmed-meshheading:10597507-Genetic Testing,
pubmed-meshheading:10597507-Genome,
pubmed-meshheading:10597507-Genotype,
pubmed-meshheading:10597507-Humans,
pubmed-meshheading:10597507-Models, Genetic,
pubmed-meshheading:10597507-Nuclear Family,
pubmed-meshheading:10597507-Quantitative Trait, Heritable
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pubmed:year |
1999
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pubmed:articleTitle |
Environmental covariates: effects on the power of sib-pair linkage methods.
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pubmed:affiliation |
Department of Medicine, Louisiana State University Medical Center, New Orleans, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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