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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3-4
|
| pubmed:dateCreated |
1976-3-1
|
| pubmed:abstractText |
Tumor-specific transplantation immunity was demonstrated in syngenic rats immunized and challenged with tumor cells (T9) from an N-methyl N-nitrosourea-induced brain tumor. All unimmunized rats and rats pretreated with normal glial cells in complete Freund's adjuvant or with adjuvant alone died of intracerebral (i.c.) neoplasia at approximately 3 weeks post-challenge. Rats which were immunized with T9 cells with or without adjuvant failed to develop i.c. tumors by 6 weeks even though the challenge dose was 2 logs greater than a dose which consistently resulted in neoplasia in unimmunized rats.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0025-7850
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
6
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
249-59
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1059719-Animals,
pubmed-meshheading:1059719-Antigen-Antibody Reactions,
pubmed-meshheading:1059719-Antigens, Neoplasm,
pubmed-meshheading:1059719-Astrocytoma,
pubmed-meshheading:1059719-Brain Neoplasms,
pubmed-meshheading:1059719-Disease Models, Animal,
pubmed-meshheading:1059719-Freund's Adjuvant,
pubmed-meshheading:1059719-Immunotherapy,
pubmed-meshheading:1059719-Methylnitrosourea,
pubmed-meshheading:1059719-Neoplasm Transplantation,
pubmed-meshheading:1059719-Rats,
pubmed-meshheading:1059719-Transplantation, Homologous,
pubmed-meshheading:1059719-Transplantation Immunology
|
| pubmed:year |
1975
|
| pubmed:articleTitle |
Tumor-specific transplantation immunity to intracerebral challenge with cells from a methylnitrosourea- induced brain tumor.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|