rdf:type |
|
lifeskim:mentions |
umls-concept:C0032143,
umls-concept:C0087111,
umls-concept:C0205178,
umls-concept:C0282440,
umls-concept:C0332162,
umls-concept:C0520997,
umls-concept:C0948008,
umls-concept:C1096777,
umls-concept:C1442467,
umls-concept:C1457887,
umls-concept:C2603343
|
pubmed:issue |
21
|
pubmed:dateCreated |
1999-12-14
|
pubmed:abstractText |
Recombinant tissue-type plasminogen activator (rt-PA) improves outcomes for patients with acute ischemic stroke, but current approved use is limited to within 3 hours of symptom onset. This restricts the number of patients who can be treated, since most stroke patients present more than 3 hours after symptom onset.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0098-7484
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
282
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2019-26
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10591384-Aged,
pubmed-meshheading:10591384-Brain Ischemia,
pubmed-meshheading:10591384-Cerebrovascular Disorders,
pubmed-meshheading:10591384-Double-Blind Method,
pubmed-meshheading:10591384-Female,
pubmed-meshheading:10591384-Fibrinolytic Agents,
pubmed-meshheading:10591384-Humans,
pubmed-meshheading:10591384-Male,
pubmed-meshheading:10591384-Middle Aged,
pubmed-meshheading:10591384-Severity of Illness Index,
pubmed-meshheading:10591384-Survival Analysis,
pubmed-meshheading:10591384-Thrombolytic Therapy,
pubmed-meshheading:10591384-Time Factors,
pubmed-meshheading:10591384-Tissue Plasminogen Activator,
pubmed-meshheading:10591384-Treatment Outcome
|
pubmed:year |
1999
|
pubmed:articleTitle |
Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset. The ATLANTIS Study: a randomized controlled trial. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke.
|
pubmed:affiliation |
Oregon Stroke Center, Portland 97201, USA. clarkw@ohsu.edu
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase III
|