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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1999-12-28
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pubmed:databankReference |
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pubmed:abstractText |
The formation of the root epidermis of Arabidopsis provides a simple and elegant model for the analysis of cell patterning. A novel gene, WEREWOLF (WER), is described here that is required for position-dependent patterning of the epidermal cell types. The WER gene encodes a MYB-type protein and is preferentially expressed within cells destined to adopt the non-hair fate. Furthermore, WER is shown to regulate the position-dependent expression of the GLABRA2 homeobox gene, to interact with a bHLH protein, and to act in opposition to the CAPRICE MYB. These results suggest a simple model to explain the specification of the two root epidermal cell types, and they provide insight into the molecular mechanisms used to control cell patterning.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ATR1 protein, Arabidopsis,
http://linkedlifedata.com/resource/pubmed/chemical/Arabidopsis Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/CPC protein, Arabidopsis,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/GL2 protein, Arabidopsis,
http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-myb
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0092-8674
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
24
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pubmed:volume |
99
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
473-83
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pubmed:dateRevised |
2006-11-20
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pubmed:meshHeading |
pubmed-meshheading:10589676-Amino Acid Sequence,
pubmed-meshheading:10589676-Arabidopsis,
pubmed-meshheading:10589676-Arabidopsis Proteins,
pubmed-meshheading:10589676-Cell Lineage,
pubmed-meshheading:10589676-Cloning, Molecular,
pubmed-meshheading:10589676-DNA-Binding Proteins,
pubmed-meshheading:10589676-Gene Expression Regulation, Plant,
pubmed-meshheading:10589676-Genes, Homeobox,
pubmed-meshheading:10589676-Genes, Plant,
pubmed-meshheading:10589676-Genes, Regulator,
pubmed-meshheading:10589676-Homeodomain Proteins,
pubmed-meshheading:10589676-Hypocotyl,
pubmed-meshheading:10589676-Models, Biological,
pubmed-meshheading:10589676-Molecular Sequence Data,
pubmed-meshheading:10589676-Plant Proteins,
pubmed-meshheading:10589676-Plant Roots,
pubmed-meshheading:10589676-Proto-Oncogene Proteins c-myb,
pubmed-meshheading:10589676-Sequence Homology, Amino Acid,
pubmed-meshheading:10589676-Tissue Distribution
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pubmed:year |
1999
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pubmed:articleTitle |
WEREWOLF, a MYB-related protein in Arabidopsis, is a position-dependent regulator of epidermal cell patterning.
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pubmed:affiliation |
Department of Biology, University of Michigan, Ann Arbor 48109-1048, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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