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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2000-1-13
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pubmed:abstractText |
Asthma is characterized by airflow obstruction, inflammatory cell infiltration, and the synthesis of mediators, such as T(H2) cytokines and leukotrienes, in the airways. Cysteinyl leukotriene (cysLT) receptor antagonists have recently been associated with clinical improvement of asthma and reduced airway inflammation. Whether the beneficial effects of cysLT antagonists are mediated through the modulation of cytokine expression has not been determined.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0091-6749
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
104
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1147-54
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10588994-Acetates,
pubmed-meshheading:10588994-Airway Resistance,
pubmed-meshheading:10588994-Animals,
pubmed-meshheading:10588994-Antigens,
pubmed-meshheading:10588994-Area Under Curve,
pubmed-meshheading:10588994-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:10588994-Eosinophils,
pubmed-meshheading:10588994-Gene Expression,
pubmed-meshheading:10588994-Immunohistochemistry,
pubmed-meshheading:10588994-Immunophenotyping,
pubmed-meshheading:10588994-In Situ Hybridization,
pubmed-meshheading:10588994-Interleukin-5,
pubmed-meshheading:10588994-Leukotriene Antagonists,
pubmed-meshheading:10588994-Lung,
pubmed-meshheading:10588994-Myelin Basic Proteins,
pubmed-meshheading:10588994-Ovalbumin,
pubmed-meshheading:10588994-Quinolines,
pubmed-meshheading:10588994-RNA, Messenger,
pubmed-meshheading:10588994-Rats,
pubmed-meshheading:10588994-Rats, Inbred BN
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pubmed:year |
1999
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pubmed:articleTitle |
Montelukast, a leukotriene receptor antagonist, inhibits the late airway response to antigen, airway eosinophilia, and IL-5-expressing cells in Brown Norway rats.
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pubmed:affiliation |
Meakins-Christie Laboratories and Montreal Chest Institute Research Center, McGill University, Montreal, Quebec, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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