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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2000-1-11
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pubmed:abstractText |
The floral homeotic gene AGAMOUS specifies stamen and carpel fate in the central whorls of Arabidopsis flowers. Transcription of AGAMOUS RNA is restricted to the center of developing flowers by several, partially redundant negative regulators, one of which is the homeotic gene APETALA2. We have identified regulatory elements that mediate transcriptional repression of AGAMOUS by APETALA2 and found that several redundant elements respond independently to loss of APETALA2 activity. Thus, redundancy at the level of cis-regulatory sequences is independent of redundancy at the level of trans-regulators. We have also found that only the early, but not the late, effects of APETALA2 on AGAMOUS require the meristem-identity protein LEAFY, a positive regulator of AGAMOUS.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/AGAMOUS Protein, Arabidopsis,
http://linkedlifedata.com/resource/pubmed/chemical/APETALA2 protein, Arabidopsis,
http://linkedlifedata.com/resource/pubmed/chemical/Arabidopsis Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/LFY protein, Arabidopsis,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Plant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Repressor Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0012-1606
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 1999 Academic Press.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
216
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
260-4
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10588876-AGAMOUS Protein, Arabidopsis,
pubmed-meshheading:10588876-Arabidopsis,
pubmed-meshheading:10588876-Arabidopsis Proteins,
pubmed-meshheading:10588876-Cells, Cultured,
pubmed-meshheading:10588876-DNA-Binding Proteins,
pubmed-meshheading:10588876-Enhancer Elements, Genetic,
pubmed-meshheading:10588876-Gene Expression Regulation, Plant,
pubmed-meshheading:10588876-Genes, Reporter,
pubmed-meshheading:10588876-Histocytochemistry,
pubmed-meshheading:10588876-Homeodomain Proteins,
pubmed-meshheading:10588876-In Situ Hybridization,
pubmed-meshheading:10588876-Nuclear Proteins,
pubmed-meshheading:10588876-Plant Proteins,
pubmed-meshheading:10588876-RNA, Messenger,
pubmed-meshheading:10588876-Regulatory Sequences, Nucleic Acid,
pubmed-meshheading:10588876-Repressor Proteins,
pubmed-meshheading:10588876-Transcription Factors
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pubmed:year |
1999
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pubmed:articleTitle |
Redundant enhancers mediate transcriptional repression of AGAMOUS by APETALA2.
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pubmed:affiliation |
Plant Biology Laboratory, The Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, 92037, California.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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