Linked Life Data

10587014

Source:http://linkedlifedata.com/resource/pubmed/id/10587014

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2000-2-15
pubmed:abstractText
To test the adequacy of equal energy principle (EEP), guinea pigs were exposed to impact tone. The changes in electrophysiological data, namely endocochlear potential (EP) and the change in K+ ion and Na+ ion concentrations in the endolymph were investigated. The frequency of impact tone was 1 pulse/second or 1 pulse/3 seconds. The steady state tone had Leq24h = 100, 95, 90 or 85 dB, and impact tone had Leq24h = 95, 90 or 85 dB. The results are the following. Both steady state and impact tone exposure cause changes of electrophysiological data. The effects on the absolute value of negative EP induced by impact tone exposures were smaller than that of steady state tone of the same Leq. The rate of pulses was also an important factor for impact tone exposure. Impact tone exposure of 1 pulse/second caused smaller absolute value of negative EP than that of 1 pulse/3 seconds. The K+ ion concentration time course in the endolymph remained similar to the control (Exp. 1) only in Exp. 8 (85 dB; the lowest steady state noise exposure in our experiments), but no decrease in the K+ ion concentration was detected in the other experiments, suggesting an alteration in the K+ ion flow. The Na+ ion concentration time course was also influenced showing no increase in Na+ ion concentration compared to the control (Exp. 1c) and the lowest steady-state exposure experiment (Exp. 8c). Our experimental results suggest that both the K+ ion and Na+ ion movement are altered by tone exposure. We found also that the different types of noise exposure with the same Leq value does not exhibit the same changes. Leq24h is not an accurate damage risk criteria.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0040-8727
pubmed:author
pubmed:issnType
Print
pubmed:volume
188
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
227-38
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Comparative study of effects of impact tone and steady state tone exposure: EP and concentration of K+ ion and Na+ ion.
pubmed:affiliation
Department of Hygiene, Asahikawa Medical College, Hokkaido, Japan.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't