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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2000-2-4
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pubmed:databankReference |
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pubmed:abstractText |
We report the identification of a new transcript homologous to the Drosophila staufen protein. This transcript, named STAU2 (HGMW-approved gene symbol and name), maps to the chromosome 8q13-q21 region. The full-length STAU2 cDNA is 4058 bp and contains an open reading frame of 479 amino acids. Analysis of the predicted protein product indicated the presence of three double-stranded RNA-binding domains. Best-fit analysis revealed a 48.5% similarity to the Drosophila protein and a 59.9% similarity to the recently described mammalian homolog hStau, indicating that at least two different transcripts with homologies to the fly protein are present in mammals.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0888-7543
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 1999 Academic Press.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
113-8
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pubmed:dateRevised |
2008-10-15
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pubmed:meshHeading |
pubmed-meshheading:10585778-Amino Acid Sequence,
pubmed-meshheading:10585778-Animals,
pubmed-meshheading:10585778-Base Sequence,
pubmed-meshheading:10585778-Binding Sites,
pubmed-meshheading:10585778-Chromosomes, Human, Pair 8,
pubmed-meshheading:10585778-DNA, Complementary,
pubmed-meshheading:10585778-Drosophila Proteins,
pubmed-meshheading:10585778-Drosophila melanogaster,
pubmed-meshheading:10585778-Expressed Sequence Tags,
pubmed-meshheading:10585778-Gene Duplication,
pubmed-meshheading:10585778-Gene Expression,
pubmed-meshheading:10585778-Genes,
pubmed-meshheading:10585778-Genetic Diseases, Inborn,
pubmed-meshheading:10585778-Humans,
pubmed-meshheading:10585778-Mammals,
pubmed-meshheading:10585778-Molecular Sequence Data,
pubmed-meshheading:10585778-Open Reading Frames,
pubmed-meshheading:10585778-Protein Structure, Tertiary,
pubmed-meshheading:10585778-RNA,
pubmed-meshheading:10585778-RNA-Binding Proteins,
pubmed-meshheading:10585778-Sequence Alignment,
pubmed-meshheading:10585778-Sequence Homology,
pubmed-meshheading:10585778-Species Specificity
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pubmed:year |
1999
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pubmed:articleTitle |
Identification of a novel homolog of the Drosophila staufen protein in the chromosome 8q13-q21.1 region.
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pubmed:affiliation |
Telethon Institute of Genetics and Medicine (TIGEM), San Raffaele Biomedical Science Park, Milan, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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