|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001811,
umls-concept:C0014406,
umls-concept:C0033572,
umls-concept:C0038317,
umls-concept:C0086418,
umls-concept:C0205462,
umls-concept:C0392747,
umls-concept:C0392762,
umls-concept:C0443172,
umls-concept:C0486616,
umls-concept:C0521115,
umls-concept:C0521425,
umls-concept:C0936012,
umls-concept:C1522384,
umls-concept:C1522721,
umls-concept:C1705165,
umls-concept:C1707455,
umls-concept:C1710706,
umls-concept:C2700061
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
2000-1-10
|
|
pubmed:abstractText |
It is well-known that the incidence of benign prostatic hyperplasia (BPH) increases with aging. The age-dependent changes in the ratio of serum sex steroid concentrations may play a role in BPH development. To clarify the relationship between the prostatic tissue concentrations of these steroids and age, we established a precise method of simultaneous quantitative analysis for prostatic sex steroids and used this method to investigate the tissue concentrations of three major sex steroids (testosterone, dihydrotestosterone, and estradiol) in the human prostate.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0270-4137
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright 2000 Wiley-Liss, Inc.
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
42
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
45-55
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10579798-Aged,
pubmed-meshheading:10579798-Aging,
pubmed-meshheading:10579798-Animals,
pubmed-meshheading:10579798-Dihydrotestosterone,
pubmed-meshheading:10579798-Endocrine Glands,
pubmed-meshheading:10579798-Estradiol,
pubmed-meshheading:10579798-Gonadal Steroid Hormones,
pubmed-meshheading:10579798-Humans,
pubmed-meshheading:10579798-Male,
pubmed-meshheading:10579798-Prostate,
pubmed-meshheading:10579798-Rats,
pubmed-meshheading:10579798-Testosterone
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Changes in the endocrine environment of the human prostate transition zone with aging: simultaneous quantitative analysis of prostatic sex steroids and comparison with human prostatic histological composition.
|
|
pubmed:affiliation |
Department of Urology, Gunma University School of Medicine, Maebashi, Japan. yshibata@akagi.sb.gunma-u.ac.jp
|
|
pubmed:publicationType |
Journal Article,
Comparative Study
|
