Source:http://linkedlifedata.com/resource/pubmed/id/10575734
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2000-1-27
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pubmed:abstractText |
The synthesis of the title compound via the Hantzsch method from 4'-flavone carboxaldehyde is described, and its molecular structure was determined by X-ray crystallography. The 1,4-dihydropyridine (1,4-DHP) ring adopts a boat conformation. The phenyl ring of the flavone is not exactly perpendicular to the DHP ring. Calcium antagonistic activity of this compound was evaluated in vitro by using BaCl2-stimulated rat ileum.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0014-827X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
660-5
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:10575734-Animals,
pubmed-meshheading:10575734-Calcium Channel Blockers,
pubmed-meshheading:10575734-Dihydropyridines,
pubmed-meshheading:10575734-Female,
pubmed-meshheading:10575734-Male,
pubmed-meshheading:10575734-Molecular Conformation,
pubmed-meshheading:10575734-Rats,
pubmed-meshheading:10575734-X-Ray Diffraction
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pubmed:year |
1999
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pubmed:articleTitle |
Synthesis and X-ray crystal structure of the calcium channel antagonist: dimethyl 1,4-dihydro-2,6-dimethyl-4-[4'-(4H-4-oxo-1-benzopyran-2-yl)phenyl]- 3,5-pyridine dicarboxylate.
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pubmed:affiliation |
Department of Pharmaceutical Chemistry, Ankara University, Faculty of Pharmacy, Turkey.
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pubmed:publicationType |
Journal Article
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