| pubmed-article:10575085 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10575085 | lifeskim:mentions | umls-concept:C0011065 | lld:lifeskim |
| pubmed-article:10575085 | lifeskim:mentions | umls-concept:C0063695 | lld:lifeskim |
| pubmed-article:10575085 | lifeskim:mentions | umls-concept:C0521390 | lld:lifeskim |
| pubmed-article:10575085 | lifeskim:mentions | umls-concept:C0022116 | lld:lifeskim |
| pubmed-article:10575085 | lifeskim:mentions | umls-concept:C0011155 | lld:lifeskim |
| pubmed-article:10575085 | lifeskim:mentions | umls-concept:C2348867 | lld:lifeskim |
| pubmed-article:10575085 | lifeskim:mentions | umls-concept:C0205374 | lld:lifeskim |
| pubmed-article:10575085 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:10575085 | pubmed:dateCreated | 1999-12-21 | lld:pubmed |
| pubmed-article:10575085 | pubmed:abstractText | Recent studies have shown a crucial role of intercellular adhesion molecule 1 (ICAM-1) in expansion of infarction after focal cerebral ischemia. The purpose of the present study was to assess whether ICAM-1 is involved in selective neuronal vulnerability and reactive gliosis after transient forebrain ischemia. ICAM-1 knockout mice and wild-type mice were subjected to transient forebrain ischemia for 5, 10 or 15 min, and the hippocampus and caudoputamen were examined 7 days later with conventional histological and immunohistochemical methods. Bilateral common carotid artery occlusion with less than 10% of baseline cortical microperfusion for 10 or 15 min resulted in ischemic neuronal damage in the hippocampus and caudoputamen. The frequency and the severity of neuronal damage were similar in wild-type and knockout mice. Proliferation of reactive astrocytes in the hippocampus was also similar in both types of mice. Therefore, it is highly unlikely that ICAM-1 plays a key role in delayed neuronal death after transient global ischemia or in astroglial responses after ischemic neuronal injury. | lld:pubmed |
| pubmed-article:10575085 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10575085 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10575085 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10575085 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10575085 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10575085 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10575085 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:10575085 | pubmed:issn | 0006-8993 | lld:pubmed |
| pubmed-article:10575085 | pubmed:author | pubmed-author:MatsumotoMM | lld:pubmed |
| pubmed-article:10575085 | pubmed:author | pubmed-author:KitagawaKK | lld:pubmed |
| pubmed-article:10575085 | pubmed:author | pubmed-author:HoriMM | lld:pubmed |
| pubmed-article:10575085 | pubmed:author | pubmed-author:YanagiharaTT | lld:pubmed |
| pubmed-article:10575085 | pubmed:author | pubmed-author:KuwabaraKK | lld:pubmed |
| pubmed-article:10575085 | pubmed:author | pubmed-author:OhtsukiTT | lld:pubmed |
| pubmed-article:10575085 | pubmed:author | pubmed-author:MabuchiTT | lld:pubmed |
| pubmed-article:10575085 | pubmed:author | pubmed-author:YagitaYY | lld:pubmed |
| pubmed-article:10575085 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10575085 | pubmed:day | 20 | lld:pubmed |
| pubmed-article:10575085 | pubmed:volume | 847 | lld:pubmed |
| pubmed-article:10575085 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10575085 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10575085 | pubmed:pagination | 166-74 | lld:pubmed |
| pubmed-article:10575085 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:meshHeading | pubmed-meshheading:10575085... | lld:pubmed |
| pubmed-article:10575085 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10575085 | pubmed:articleTitle | Deficiency of intercellular adhesion molecule 1 fails to mitigate selective neuronal death after transient global ischemia. | lld:pubmed |
| pubmed-article:10575085 | pubmed:affiliation | Division of Strokology, Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine (A-8), 2-2 Yamadaoka, Suita, Japan. kitagawa@medone.med.osaka-u.ac.jp | lld:pubmed |
| pubmed-article:10575085 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10575085 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:15894 | entrezgene:pubmed | pubmed-article:10575085 | lld:entrezgene |
