Source:http://linkedlifedata.com/resource/pubmed/id/10571824
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2000-2-9
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pubmed:abstractText |
Transthyretin-Met 30 (TTR-Met 30) is a variant of transthyretin and is usually associated with familial amyloid polyneuropathy. It is rare that patients with TTR-Met 30 will primarily develop amyloid cardiomyopathy. This report presents a patient with late-onset TTR-Met 30 who primarily developed amyloid cardiomyopathy, with less amyloid polyneuropathy in the peripheral nervous system than is usually seen. An autopsy was performed, and histological examination revealed many foreign-body giant cells and macrophages in the area of amyloid deposition that was found in nearly all of the organs.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1320-5463
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
898-902
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10571824-Aged,
pubmed-meshheading:10571824-Amyloid Neuropathies,
pubmed-meshheading:10571824-Amyloidosis,
pubmed-meshheading:10571824-Base Sequence,
pubmed-meshheading:10571824-Cardiomyopathies,
pubmed-meshheading:10571824-Female,
pubmed-meshheading:10571824-Giant Cells,
pubmed-meshheading:10571824-Heart Ventricles,
pubmed-meshheading:10571824-Humans,
pubmed-meshheading:10571824-Methionine,
pubmed-meshheading:10571824-Point Mutation,
pubmed-meshheading:10571824-Prealbumin,
pubmed-meshheading:10571824-Rectum
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pubmed:year |
1999
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pubmed:articleTitle |
A case of hereditary amyloidosis transthyretin variant Met 30 with amyloid cardiomyopathy, less polyneuropathy, and the presence of giant cells.
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pubmed:affiliation |
Department of Pathology, National Cardiovascular Center, Osaka, Japan. ynakamura@mti.biglobe.ne.jp
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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