Source:http://linkedlifedata.com/resource/pubmed/id/10571175
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
20
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pubmed:dateCreated |
1999-12-23
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pubmed:abstractText |
Eleven resveratrol oligomers and six acetylated derivatives were evaluated for in vitro cytotoxicity against a panel of human tumor cell lines. The acetate of (-)-ampelopsin A (12) showed potent and selective cytotoxic activity with ED50 values of 0.6, 0.7 and 2.0 microg/mL against KB, 1A9 and MCF-7 cells, respectively. Hopeaphenol (10) and pallidol hexaacetate (13) also showed significant cytotoxicity against KB cells with ED50 values of 1.2 and 1.6 microg/mL, respectively.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3057-60
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10571175-Acetates,
pubmed-meshheading:10571175-Biopolymers,
pubmed-meshheading:10571175-Cell Division,
pubmed-meshheading:10571175-Drug Screening Assays, Antitumor,
pubmed-meshheading:10571175-Humans,
pubmed-meshheading:10571175-Stilbenes,
pubmed-meshheading:10571175-Tumor Cells, Cultured
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pubmed:year |
1999
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pubmed:articleTitle |
Antitumor agents 200. Cytotoxicity of naturally occurring resveratrol oligomers and their acetate derivatives.
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pubmed:affiliation |
Natural Products Laboratory, School of Pharmacy, University of North Carolina, Chapel Hill 27599-7360, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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