Linked Life Data

10568065

Source:http://linkedlifedata.com/resource/pubmed/id/10568065

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1999-12-13
pubmed:abstractText
It is accepted now that most antiphospholipid antibodies (APA) are not directed against phospholipids alone but complexes of phospholipid-binding proteins and phospholipids. One of the phospholipid-binding proteins is beta 2-glycoprotein I (beta 2-GPI), a normal plasma glycoprotein, which under physiological conditions binds with negative charged phospholipids. Measurement of anti-beta 2-GPI antibodies requires specific tests, since ELISA for determination of anticardiolipin antibodies (ACA) may detect both antibodies directly binding cardiolipin and antibodies against cardiolipin-binding proteins. In this study a comparison of APAs against cardiolipin (CL), phosphatidylserine (PS), phosphatidylinositol (PI), phosphatidylethanolamine (PE) v.s. anti-beta 2-GPI were compared.
pubmed:language
cze
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1210-7832
pubmed:author
pubmed:issnType
Print
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
255-61
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
[Comparative study of the occurrence of beta-2-glycoprotein I antibodies (anti-beta-2-GPI) and anticardiolipin antibodies (ACA) in the blood of pregnant women].
pubmed:affiliation
1. ústav lékarské chemie a biochemie 1. LF UK, Praha.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract, Research Support, Non-U.S. Gov't