Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5444
pubmed:dateCreated
1999-12-9
pubmed:abstractText
Neurokinin-1 receptor (NK1R) and mu-opioid receptor (muOR) agonists affected respiratory rhythm when injected directly into the preBötzinger Complex (preBötC), the hypothesized site for respiratory rhythmogenesis in mammals. These effects were mediated by actions on preBötC rhythmogenic neurons. The distribution of NK1R+ neurons anatomically defined the preBötC. Type 1 neurons in the preBötC, which have rhythmogenic properties, expressed both NK1Rs and muORs, whereas type 2 neurons expressed only NK1Rs. These findings suggest that the preBötC is a definable anatomic structure with unique physiological function and that a subpopulation of neurons expressing both NK1Rs and muORs generate respiratory rhythm and modulate respiratory frequency.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-10400966, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-10400967, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-10432113, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-1304324, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-1683005, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-2332528, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-2332529, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-2476055, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-2858889, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-3288108, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-3737299, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-7798382, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-7831394, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-8283211, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-8714653, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-8714654, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-8806921, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-8815217, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-9044468, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-9114241, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-9225492, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-9504127, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-9508848, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-9558470, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-9692751, http://linkedlifedata.com/resource/pubmed/commentcorrection/10567264-9875360
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
19
pubmed:volume
286
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1566-8
pubmed:dateRevised
2011-5-13
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Modulation of respiratory frequency by peptidergic input to rhythmogenic neurons in the preBötzinger complex.
pubmed:affiliation
Department of Neurobiology, University of California Los Angeles, Box 951763, Los Angeles, CA 90095-1763, USA.
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't