Linked Life Data

10562719

Source:http://linkedlifedata.com/resource/pubmed/id/10562719

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1999-12-14
pubmed:abstractText
Staphylococcal infections cause a number of serious diseases, ranging from acute septicaemia to chronic problems such as osteomyelitis and septic arthritis. Resistance to antibiotics is a growing problem and has re-ignited interest in vaccines and in passive immunization with antibodies. Natural infections and vaccines based on whole bacteria lead to poor antibody responses, but recent research using animal models of several staphylococcal diseases reveals that vaccines based on recombinant staphylococcal extracellular-matrix-binding proteins are much more protective. Passive immunization with antibodies against one of these proteins (collagen-binding protein) also shows promise in a mouse model of sepsis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1357-4310
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
532-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Extracellular-matrix-binding proteins as targets for the prevention of Staphylococcus aureus infections.
pubmed:affiliation
Karolinska Institutet, Department of Immunology, Microbiology, Pathology and Infectious Diseases, Huddinge University Hospital, F82. S-141 86 Huddinge, Sweden. jan-ingmar.flock@impi.ki.se
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't