Source:http://linkedlifedata.com/resource/pubmed/id/10555916
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1999-12-17
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pubmed:abstractText |
We describe the use of antibodies to RNA polymerase III in the diagnosis of scleroderma in 2 patients who presented with renal crisis without other clinical features of the condition. Both presented with accelerated hypertension, rapidly progressive acute renal failure, microangiopathic hemolytic anemia, and thrombocytopenia. One patient developed digital infarcts in the course of his initial illness. Neither showed evidence of skin thickening at presentation. Nailfold capillaroscopy was normal in one patient and showed capillary dropout in the other. Renal biopsy showed findings consistent with thrombotic microangiopathy and both had anti-RNA polymerase III antibodies.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0315-162X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2489-92
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:10555916-Autoantibodies,
pubmed-meshheading:10555916-Biological Markers,
pubmed-meshheading:10555916-Humans,
pubmed-meshheading:10555916-Hypertension,
pubmed-meshheading:10555916-Male,
pubmed-meshheading:10555916-Middle Aged,
pubmed-meshheading:10555916-RNA Polymerase III,
pubmed-meshheading:10555916-Renal Insufficiency,
pubmed-meshheading:10555916-Scleroderma, Systemic
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pubmed:year |
1999
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pubmed:articleTitle |
Anti-RNA polymerase III antibodies in the diagnosis of scleroderma renal crisis sine scleroderma.
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pubmed:affiliation |
Department of Clinical Immunology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia. tri@immu.rpa.cs.nsw.gov.au
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pubmed:publicationType |
Journal Article,
Case Reports
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