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pubmed-article:10551597pubmed:abstractTextCholinergic agents produce analgesia after systemic and intrathecal administration. A retrospective review showed that intrathecal neostigmine was more potent in women than in men, suggesting a sex difference in this response. The purpose of this study was to determine whether such a sex difference exists in normal rats and to examine the pharmacologic mechanisms that underlie this difference.lld:pubmed
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pubmed-article:10551597pubmed:articleTitleSex differences in cholinergic analgesia I: a supplemental nicotinic mechanism in normal females.lld:pubmed
pubmed-article:10551597pubmed:affiliationDepartment of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1009, USA.lld:pubmed
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