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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1999-11-24
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pubmed:abstractText |
Cholinergic agents produce analgesia after systemic and intrathecal administration. A retrospective review showed that intrathecal neostigmine was more potent in women than in men, suggesting a sex difference in this response. The purpose of this study was to determine whether such a sex difference exists in normal rats and to examine the pharmacologic mechanisms that underlie this difference.
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pubmed:grant |
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pubmed:language |
eng
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|
pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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|
pubmed:month |
Nov
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|
pubmed:issn |
0003-3022
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1447-54
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10551597-Analgesics,
pubmed-meshheading:10551597-Animals,
pubmed-meshheading:10551597-Cholinergic Agents,
pubmed-meshheading:10551597-Dose-Response Relationship, Drug,
pubmed-meshheading:10551597-Female,
pubmed-meshheading:10551597-Injections, Spinal,
pubmed-meshheading:10551597-Male,
pubmed-meshheading:10551597-Muscarinic Agonists,
pubmed-meshheading:10551597-Muscarinic Antagonists,
pubmed-meshheading:10551597-Neostigmine,
pubmed-meshheading:10551597-Nicotinic Agonists,
pubmed-meshheading:10551597-Nicotinic Antagonists,
pubmed-meshheading:10551597-Pain Measurement,
pubmed-meshheading:10551597-Rats,
pubmed-meshheading:10551597-Rats, Sprague-Dawley,
pubmed-meshheading:10551597-Receptors, Nicotinic,
pubmed-meshheading:10551597-Reference Values,
pubmed-meshheading:10551597-Sex Factors
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pubmed:year |
1999
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pubmed:articleTitle |
Sex differences in cholinergic analgesia I: a supplemental nicotinic mechanism in normal females.
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pubmed:affiliation |
Department of Anesthesiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1009, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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