Linked Life Data

10549097

Source:http://linkedlifedata.com/resource/pubmed/id/10549097

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1999-12-14
pubmed:abstractText
Q fever usually presents with high fever, headache and an atypical pneumonia. A case report of a 47-year-old patient with an atypical course of a coxiella infection is described. The dominant clinical symptoms were a liver and bone marrow involvement, whereas pulmonary manifestations were absent. The diagnosis of Q fever in this patient was based on the detection of cytoplasmatic inclusion bodies in macrophages and granulocytes. Furthermore fibrin-ring granulomas ("doughnut lesions") were found in liver tissue specimen and epitheloid-cell granulomas were detected in bone marrow specimen. Complement-fixation antibody titers and PCR resulted unspecific or negative on different occasions during the course of the disease. A confirmation of the diagnosis by complement-fixation antibody test was possible only after recovery from the disease. In Q fever with atypical clinical and serological presentation the screening of blood cells for inclusion bodies and liver or bone marrow tissue for granulomas may be important for establishing the diagnosis.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0044-2771
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1019-23
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
[Sheep, chills and "doughnut granuloma"--an atypical course of Coxiella infection].
pubmed:affiliation
Klinik für Gastroenterologie, Hepatologie und Infektiologie, Heinrich-Heine-Universität Düsseldorf.
pubmed:publicationType
Journal Article, English Abstract, Case Reports