Linked Life Data

10547689

Source:http://linkedlifedata.com/resource/pubmed/id/10547689

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1999-12-6
pubmed:abstractText
Apoptosis is a highly regulated process of cell death that is required for the development and homeostasis of multicellular organisms. In contrast to necrosis, apoptosis eliminates individual cells without inducing an inflammatory response. Activation or prevention of cell death could be a critical factor in the outcome of an infection. Programmed cell death has been observed as a response to infection by a wide range of animal and plant pathogens and is mediated by an array of pathogen-encoded virulence determinants. Pathogen-induced modulation of the host cell-death pathway may serve to eliminate key immune cells or evade host defenses that can act to limit the infection. Alternatively, suppression of the death pathway may facilitate the proliferation of intracellular pathogens.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0066-4227
pubmed:author
pubmed:issnType
Print
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
155-87
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
The induction of apoptosis by bacterial pathogens.
pubmed:affiliation
Department of Microbiology, Skirball Institute, New York University School of Medicine, New York 10016, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review